Important It is possible that the main title of the report Hypothyroidism is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.
Hypothyroidism is a condition characterized by abnormally decreased activity of the thyroid gland and deficient production of thyroid hormones. The thyroid gland secretes hormones that play an essential role in regulating growth, maturation, and the rate of metabolism.
Specific symptoms and findings associated with hypothyroidism may be variable, depending upon the age at symptom onset, the degree of thyroid hormone deficiency, and/or other factors. In many adults with hypothyroidism, the condition may be characterized by generalized fatigue and lack of energy (lethargy), muscle weakness and cramping, dryness of the skin and hair, incomplete or infrequent passing of stools (constipation), sensitivity to cold, and other symptoms. If the condition is present at birth (congenital hypothyroidism), associated symptoms and findings may become apparent during early infancy. These may include respiratory and feeding difficulties, listlessness, protrusion of the abdomen, constipation, dry skin, coarse hair, progressive accumulation of fluid within bodily tissues, and other associated abnormalities. Some affected infants may have progressive retardation of physical and mental development that becomes increasingly severe (cretinism) without early recognition of the condition and prompt treatment.
There are several different causes of hypothyroidism. The condition may result from an underlying defect that is present at birth (congenital), such as improper development (dysplasia) or absence (aplasia) of the thyroid gland or biochemical (enzymatic) abnormalities. The condition may also develop later during childhood or adulthood (acquired) due to certain underlying disorders, the use of particular medications, or surgical removal of the thyroid gland. Although hypothyroidism most frequently affects adult females, the condition occurs in both genders and may become apparent at any age.
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American Thyroid Association 6066 Leesburg Pike, Suite 550 Falls Church, VA 22041 USA Tel: (703)998-8890 Fax: (703)998-8893 Email: email@example.com Internet: http://www.thyroid.org
Hormone Health Network 8401 Connecticut Avenue Suite 900 Chevy Chase, MD 20815-5817 Fax: (310)941-0259 Tel: (800)467-6663 Email: firstname.lastname@example.org Internet: http://www.hormone.org/
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This is an abstract of a report from the National Organization for Rare Disorders (NORD). A copy of the complete report can be downloaded free from the NORD website for registered users. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational therapies (if available), and references from medical literature. For a full-text version of this topic, go to www.rarediseases.org and click on Rare Disease Database under "Rare Disease Information".
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It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report
This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.
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Last Updated: 7/11/2011 Copyright 1988, 1989, 1990, 1992, 1997, 1999, 2001 National Organization for Rare Disorders, Inc.
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