Important It is possible that the main title of the report Alveolar Soft Part Sarcoma is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.
Alveolar sarcoma of soft parts
Alveolar soft part sarcoma (ASPS) is a rare sarcoma (malignant tumor of connective tissue) of an unclear cause. It is among the least common sarcomas, representing 0.2-1 percent of large studies of soft tissue sarcomas. Since there are approximately 8000 soft-tissue sarcomas per year that arise in the United States, this means there are on the order of 15 to 80 cases nationwide each year. It is characterized by a painless mass in the leg or buttock, with a particular affinity to travel to the lungs as multiple nodules, presumably while the sarcoma itself is still small. ASPS is very rare, because it involves a specific breaking and joining event between two chromosomes, called an "unbalanced translocation". This finding is observed in essentially all ASPS examined so far. This finding cannot be passed on to children, however, as the finding occurs only in the tumor, not in the normal cells, in addition, there are no families in which multiple family members have ASPS.
Treatment is with surgery and radiation for the primary place where the sarcoma arises. For disease that travels to the lungs, sometimes surgery is possible to remove nodules, but more typically chemotherapy is the only option for treatment. This tumor tends to be resistant to standard chemotherapy, so new treatments involving new chemotherapy drugs are also a reasonable option for treatment. Interferon-alfa showed benefit in one person from Japan with ASPS. There is little other data on possible helpful chemotherapy for this tumor.
American Cancer Society, Inc. 1599 Clifton Road NE Atlanta, GA 30329 USA Tel: (404)320-3333 Tel: (800)227-2345 TDD: (866)228-4327 Internet: http://www.cancer.org
National Cancer Institute 6116 Executive Blvd MSC 8322 Room 3036A Bethesda, MD 20892-8322 USA Tel: (301)435-3848 Tel: (800)422-6237 TDD: (800)332-8615 Email: email@example.com Internet: http://www.cancer.gov
National Coalition for Cancer Survivorship 1010 Wayne Avenue 7th Floor Silver Spring, MD 20910 Tel: (301)650-9127 Fax: (301)565-9670 Tel: (888)650-9127 Email: firstname.lastname@example.org Internet: http://www.canceradvocacy.org/
Sarcoma Foundation of America 9884 Main Street Damascus, MD 20872 USA Tel: (301)253-8687 Fax: (301)253-8690 Email: email@example.com Internet: http://www.curesarcoma.org
Sarcoma Alliance 775 E. Blithedale #334 Mill Valley, CA 94941 USA Tel: (415)381-7236 Fax: (415)381-7235 Email: firstname.lastname@example.org Internet: http://www.sarcomaalliance.org
Rare Cancer Alliance 1649 North Pacana Way Green Valley, AZ 85614 USA Tel: (520)625-5495 Fax: (615)526-4921 Internet: http://www.rare-cancer.org
Alliance Against Alveolar Soft Part Sarcoma 141-08 Coolidge Ave Briarwood, NY 11435 USA Tel: (718)523-7752 Fax: (718)657-0516 Email: email@example.com Internet: http://www.alveolarspsarcoma.net/
Genetic and Rare Diseases (GARD) Information Center PO Box 8126 Gaithersburg, MD 20898-8126 Tel: (301)251-4925 Fax: (301)251-4911 Tel: (888)205-2311 TDD: (888)205-3223 Internet: http://rarediseases.info.nih.gov/GARD/
Cure Alveolar Soft Part Sarcoma International 260 Tappan St. Brookline, MA 02445 Tel: (617)731-1143 Email: firstname.lastname@example.org Internet: http://cureasps.org/
Friends of Cancer Research 1800 M Street NW Suite 1050 South Washington, DC 22202 Tel: (202)944-6700 Email: email@example.com Internet: http://www.focr.org
Cancer.Net American Society of Clinical Oncology 2318 Mill Road Suite 800 Alexandria, VA 22314 Tel: (571)483-1780 Fax: (571)366-9537 Tel: (888)651-3038 Email: firstname.lastname@example.org Internet: http://www.cancer.net/patient
Cancer Support Community 1050 17th St NW Washington, DC 20036 Tel: (202)659-9709 Fax: (202)974-7999 Tel: (888)793-9355 Internet: http://www.cancersupportcommunity.org/
Lance Armstrong Foundation 2201 E. Sixth Street Austin, TX 78702 Tel: (512)236-8820 Fax: (512)236-8482 Tel: (877)236-8820 Email: email@example.com Internet: http://www.livestrong.org
BeatSarcoma 76 Ellsworth Street San Francisco, CA 94110 Tel: (415)651-4473 Email: firstname.lastname@example.org Internet: http://www.beatsarcoma.org/
Northwest Sarcoma Foundation P.O. Box 91460 Portland, OR 97291 Tel: (503)954-5740 Email: email@example.com Internet: http://www.nwsarcoma.org
For a Complete Report
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It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report
This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.
For additional information and assistance about rare disorders, please contact the National Organization for Rare Disorders at P.O. Box 1968, Danbury, CT 06813-1968; phone (203) 744-0100; web site www.rarediseases.org or email firstname.lastname@example.org
Last Updated: 5/9/2008 Copyright 2002 National Organization for Rare Disorders, Inc.
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