Important It is possible that the main title of the report Alveolar Soft Part Sarcoma is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.
Alveolar sarcoma of soft parts
Alveolar soft part sarcoma (ASPS) is a rare sarcoma (malignant tumor of connective tissue) of an unclear cause. It is among the least common sarcomas, representing 0.2-1 percent of large studies of soft tissue sarcomas. Since there are approximately 8000 soft-tissue sarcomas per year that arise in the United States, this means there are on the order of 15 to 80 cases nationwide each year. It is characterized by a painless mass in the leg or buttock, with a particular affinity to travel to the lungs as multiple nodules, presumably while the sarcoma itself is still small. ASPS, is very rare, because it involves a specific breaking and joining event between two chromosomes, called an "unbalanced translocation". This finding is observed in essentially all ASPS examined so far. This finding cannot be passed on to children, however, as the finding occurs only in the tumor, not in the normal cells, in addition, there are no families in which multiple family members have ASPS.
Treatment is with surgery and radiation for the primary place where the sarcoma arises. For disease that travels to the lungs, sometimes surgery is possible to remove nodules, but more typically chemotherapy is the only option for treatment. This tumor tends to be resistant to standard chemotherapy, so new treatments involving new chemotherapy drugs are also a reasonable option for treatment. Interferon-alfa showed benefit in one person from Japan with ASPS. There is little other data on possible helpful chemotherapy for this tumor.
American Cancer Society, Inc. 250 Williams NW St Ste 6000 Atlanta, GA 30303 USA Tel: (404)320-3333 Tel: (800)227-2345 TDD: (866)228-4327 Internet: http://www.cancer.org
National Cancer Institute 6116 Executive Blvd Suite 300 Bethesda, MD 20892-8322 USA Tel: (301)435-3848 Tel: (800)422-6237 TDD: (800)332-8615 Email: email@example.com Internet: http://www.cancer.gov
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Sarcoma Foundation of America 9899 Main Street Ste 204 Damascus, MD 20872 USA Tel: (301)253-8687 Fax: (301)253-8690 Email: email@example.com Internet: http://www.curesarcoma.org
Sarcoma Alliance 775 E. Blithedale #334 Mill Valley, CA 94941 USA Tel: (415)381-7236 Fax: (415)381-7235 Email: firstname.lastname@example.org Internet: http://www.sarcomaalliance.org
Rare Cancer Alliance 1649 North Pacana Way Green Valley, AZ 85614 USA Internet: http://www.rare-cancer.org
Genetic and Rare Diseases (GARD) Information Center PO Box 8126 Gaithersburg, MD 20898-8126 Tel: (301)251-4925 Fax: (301)251-4911 Tel: (888)205-2311 TDD: (888)205-3223 Internet: http://rarediseases.info.nih.gov/GARD/
Cure Alveolar Soft Part Sarcoma International 260 Tappan St. Brookline, MA 02445 Tel: (617)731-1143 Email: email@example.com Internet: http://cureasps.org/
Friends of Cancer Research 1800 M Street NW Suite 1050 South Washington, DC 22202 Tel: (202)944-6700 Email: firstname.lastname@example.org Internet: http://www.focr.org
Cancer.Net American Society of Clinical Oncology 2318 Mill Road Suite 800 Alexandria, VA 22314 Tel: (571)483-1780 Fax: (571)366-9537 Tel: (888)651-3038 Email: email@example.com Internet: http://www.cancer.net/
Cancer Support Community 1050 17th St NW Suite 500 Washington, DC 20036 Tel: (202)659-9709 Fax: (202)974-7999 Tel: (888)793-9355 Internet: http://www.cancersupportcommunity.org/
Lance Armstrong Foundation 2201 E. Sixth Street Austin, TX 78702 Tel: (512)236-8820 Fax: (512)236-8482 Tel: (877)236-8820 Email: firstname.lastname@example.org Internet: http://www.livestrong.org
BeatSarcoma 76 Ellsworth Street San Francisco, CA 94110 Tel: (415)826-0474 Email: email@example.com Internet: http://www.beatsarcoma.org/
Northwest Sarcoma Foundation P.O. Box 91460 Portland, OR 97291 Tel: (503)954-5740 Email: firstname.lastname@example.org Internet: http://www.nwsarcoma.org
For a Complete Report
This is an abstract of a report from the National Organization for Rare Disorders (NORD). A copy of the complete report can be downloaded free from the NORD website for registered users. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational therapies (if available), and references from medical literature. For a full-text version of this topic, go to www.rarediseases.org and click on Rare Disease Database under "Rare Disease Information".
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It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report
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Last Updated: 5/9/2008 Copyright 2002 National Organization for Rare Disorders, Inc.
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