Blood-Clotting DisordersSkip to the navigation
Some people are born with an increased tendency to form blood clots. These are called inherited blood-clotting disorders. They are often related to:
- Mutated genes (such as factor V Leiden, factor II).
- Decreased amounts of certain proteins. These may include protein C, protein S, and antithrombin III.
- Increased levels of other substances. These may include antiphospholipid and lupus anticoagulant.
Other people get blood clots because of a health problem. Blood clots can happen after surgery or injury. And they can happen when a person doesn't move around for a long time.
There are several tests that can help find the cause of a blood clotting problem. Talk to your doctor about whether you need testing.
These tests may include:
- Protein C.
- Protein S.
- Factor V Leiden.
- Antiphospholipid antibody
- Lupus anticoagulant.
Other Works Consulted
- Lipe B, Ornstein DL (2011). Deficiencies of natural anticoagulants, protein C, protein S, and antithrombin. Circulation, 124(14): e365–e368.
Primary Medical Reviewer E. Gregory Thompson, MD - Internal Medicine
Specialist Medical Reviewer Jeffrey S. Ginsberg, MD - Hematology
Current as ofFebruary 9, 2015