Mitral valve regurgitation (MR) is the leaking or backflow of
blood through the valve between the upper left heart chamber (atrium) and the lower left heart chamber (ventricle). If serious, this condition can lead to a
backup of blood in the left atrium and the lungs, cause enlargement of and
damage to the left ventricle, and lead to heart failure.
valve regurgitation can either be ongoing (chronic) or sudden (acute). Chronic
MR develops slowly, possibly over decades, and symptoms, such as shortness of
breath, fatigue, and swelling in the feet and ankles, may never appear. Acute
MR is a medical emergency that requires urgent treatment to repair or replace
the mitral valve.
Treatment for MR includes medicines for symptoms. The valve may need to be repaired or replaced.
have mitral valve regurgitation may be at higher risk of heart valve infection
(endocarditis) especially if they have an artificial heart valve.
Rakesh K. Pai, MD, FACC - Cardiology, Electrophysiology & John A. McPherson, MD, FACC, FSCAI - Cardiology
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