Important It is possible that the main title of the report Chronic Intestinal Pseudo-obstruction is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.
chronic idiopathic intestinal pseudo-obstruction
Summary Chronic intestinal pseudo-obstruction (CIP) is a rare, potentially disabling gastrointestinal disorder characterized by abnormalities affecting the involuntary, coordinated muscular contractions (a process called peristalsis) of the gastrointestinal (GI) tract. Peristalsis propels food and other material through the digestive system under the control of nerves, pacemaker cells and hormones. CIP usually results from abnormalities affecting the muscles or nerves that are involved in peristalsis. Consequently, peristalsis becomes altered and inefficient. The symptoms of CIP resemble those caused by mechanical obstruction of the small bowel. Mechanical obstruction refers to something (such as a tumor, scar tissue, etc.) physically blocking the passage of food and other material through the GI tract. In individuals with CIP no such physical obstruction is present, hence the term pseudo-obstruction. Common symptoms include nausea, vomiting, abdominal pain, abdominal swelling (distention) and constipation. Ultimately, normal nutritional requirements cannot be met leading to unintended weight loss and malnourishment. CIP can potentially cause severe, even life-threatening complications.
Introduction There is no agreed upon classification system for CIP and proposed classification systems tend to be complex and confusing. There are also many different causes of CIP, which only adds to the confusion. The unifying concept for CIP regardless of cause is an abnormality affecting the passage of food and other material through the digestive system (gastrointestinal motility). Generally, CIP is broken down into two main forms depending on whether the disorder involves the muscles (myopathic CIP) or nerves (neuropathic CIP) of the GI tract that are involved in peristalsis. Some researchers lump enteric dysmotility together with CIP. The prognosis of this separate yet similar condition is different from CIP. This report deals solely with the strict definition of CIP as a disorder that causes an "obstruction-like" picture.
Association of Gastrointestinal Motility Disorders, Inc. 12 Roberts Drive Bedford, MA 01730 Tel: (781)275-1300 Fax: (781)275-1304 Email: email@example.com Internet: http://www.agmd-gimotility.org
Digestive Disease National Coalition 507 Capitol Court, NE Suite 200 Washington, DC 20002 Tel: (202)544-7497 Fax: (202)546-7105 Email: firstname.lastname@example.org Internet: http://www.ddnc.org
NIH/National Institute of Diabetes, Digestive & Kidney Diseases Office of Communications & Public Liaison Bldg 31, Rm 9A06 31 Center Drive, MSC 2560 Bethesda, MD 20892-2560 Tel: (301)496-3583 Email: NDDIC@info.niddk.nih.gov Internet: http://www2.niddk.nih.gov/
International Foundation for Functional Gastrointestinal Disorders 700 W. Virginia St., 201 Milwaukee, WI 53217 USA Tel: (414)964-1799 Fax: (414)964-7176 Tel: (888)964-2001 Email: email@example.com Internet: http://www.iffgd.org
Bowel Group for Kids Inc. PO Box 40 Oakdale, NSW, 2570 Austrailia Tel: 02 4659 6067 Fax: 61 2 4659 6381 Email: firstname.lastname@example.org Internet: http://www.bgk.org.au
Genetic and Rare Diseases (GARD) Information Center PO Box 8126 Gaithersburg, MD 20898-8126 Tel: (301)251-4925 Fax: (301)251-4911 Tel: (888)205-2311 TDD: (888)205-3223 Internet: http://rarediseases.info.nih.gov/GARD/
CORE 3 St. Andrews Place London, NW1 4LB United Kingdom Tel: 02074860341 Fax: 02072242012 Email: email@example.com Internet: http://www.corecharity.org.uk
Gastroparesis & Dysmotilities Association 5520 Dalhart Hill N.W. Calgary, AB, T3A 1S9 Canada Tel: 4032473215 Email: firstname.lastname@example.org Internet: http://www.digestivedistress.com
For a Complete Report
This is an abstract of a report from the National Organization for Rare Disorders (NORD). A copy of the complete report can be downloaded free from the NORD website for registered users. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational therapies (if available), and references from medical literature. For a full-text version of this topic, go to www.rarediseases.org and click on Rare Disease Database under "Rare Disease Information".
The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only. NORD recommends that affected individuals seek the advice or counsel of their own personal physicians.
It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report
This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.
For additional information and assistance about rare disorders, please contact the National Organization for Rare Disorders at P.O. Box 1968, Danbury, CT 06813-1968; phone (203) 744-0100; web site www.rarediseases.org or email email@example.com
Last Updated: 1/5/2012 Copyright 1987, 1988, 1989, 1994, 2003, 2012 National Organization for Rare Disorders, Inc.
How this information was developed to help you make better health decisions.
Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.