Thrombolytics are medicines that rapidly dissolve a blood clot. They might be used to treat deep vein thrombosis if it is causing severe symptoms.
These medicines are used in the hospital. They are
given through a vein in the hand or arm.
Or a doctor might use a special tube called a catheter and give the medicine directly into the
These medicines can greatly increase the
risk of bleeding, so they are used only in very specific situations where the
risk of bleeding can be balanced against the risks of not dissolving the blood
clot rapidly. Thrombolytics may reduce the incidence of
post-thrombotic syndrome in people who are at high risk
for this condition.
Guyatt GH, et al. (2012). Executive summary: Antithrombotic therapy and prevention of thrombosis, 9th ed.—American College of Chest Physicians evidence-based clinical practice guidelines. Chest, 141(2, Suppl): 7S–47S.
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