Scleroderma is a rare disease in which a person's immune system
begins to destroy normal, healthy tissues (autoimmune disease). As a result,
connective tissue of the skin, lungs, and internal organs—especially the
esophagus, kidneys, and digestive tract—is replaced with scar tissue. This
change causes the tissues to become stiff and the muscles to not work as
How this information was developed to help you make better health decisions.