Important It is possible that the main title of the report Ulcerative Colitis is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.
Chronic Non-Specific Ulcerative Colitis
Idiopathic Non-Specific Ulcerative Colitis
Inflammatory Bowel Disease (IBD), Ulcerative Colitis Type
Ulcerative colitis is an inflammatory bowel disease (IBD) of unknown cause. It is characterized by chronic inflammation and ulceration of the lining of the major portion of the large intestine (colon). In most affected individuals, the lowest region of the large intestine, known as the rectum, is initially affected. As the disease progresses, some or all, of the colon may become involved. Although associated symptoms and findings usually become apparent during adolescence or young adulthood, some individuals may experience an initial episode between ages 50 to 70. In other cases, symptom onset may occur as early as the first year of life.
Ulcerative colitis is usually a chronic disease with repeated episodes of symptoms and remission (relapsing-remitting). However, some affected individuals may have few episodes, whereas others may have severe, continuous symptoms. During an episode, affected individuals may experience attacks of watery diarrhea that may contain pus, blood, and/or mucus; abdominal pain; fever and chills; weight loss; and/or other symptoms and findings. In severe cases, individuals may be at risk for certain serious complications.
For example, severe inflammation and ulceration may result in thinning of the wall of the colon, causing tearing (perforation) of the colon and potentially life-threatening complications. In addition, in some cases, individuals with the disorder may eventually develop more generalized (systemic) symptoms, such as certain inflammatory skin or eye conditions; inflammation, pain, and swelling of certain joints (arthritis); chronic inflammation of the liver (chronic active hepatitis); and/or other findings.
The specific underlying cause of ulcerative colitis is unknown. However, genetic, immunologic, infectious, and/or psychologic factors are thought to play some causative role.
American Autoimmune Related Diseases Association, Inc. 22100 Gratiot Ave. Eastpointe, MI 48021 Tel: (586)776-3900 Fax: (586)776-3903 Tel: (800)598-4668 Email: email@example.com Internet: http://www.aarda.org/
Crohn's and Colitis Foundation of America 386 Park Avenue South 17th Floor New York, NY 10016-7374 USA Tel: (212)685-3440 Fax: (212)779-4098 Tel: (800)932-2423 Email: firstname.lastname@example.org Internet: http://www.ccfa.org
NIH/National Institute of Diabetes, Digestive & Kidney Diseases Office of Communications & Public Liaison Bldg 31, Rm 9A06 31 Center Drive, MSC 2560 Bethesda, MD 20892-2560 Tel: (301)496-3583 Email: NDDIC@info.niddk.nih.gov Internet: http://www2.niddk.nih.gov/
International Foundation for Functional Gastrointestinal Disorders 700 W. Virginia St., 201 Milwaukee, WI 53217 USA Tel: (414)964-1799 Fax: (414)964-7176 Tel: (888)964-2001 Email: email@example.com Internet: http://www.iffgd.org
Gastro-Intestinal Research Foundation 70 East Lake Street Suite 1015 Chicago, IL 60601 Tel: (312)332-1350 Fax: (312)332-4757 Email: firstname.lastname@example.org Internet: http://www.girf.org
Pull-Thru Network 1705 Wintergreen Parkway Normal, IL 61761 USA Tel: (309)262-2930 Email: PullthruNetwork@gmail.com Internet: http://www.PullthruNetwork.org
Reach Out for Youth with Ileitis and Colitis, Inc. PO Box 857 Bellmore, NY 11710 USA Tel: (631)293-3102 Email: email@example.com Internet: http://www.reachoutforyouth.org
Erythema Nodosum Yahoo Support Group Internet: http://health.groups.yahoo.com/group/erythema_nodosum_Group/
Genetic and Rare Diseases (GARD) Information Center PO Box 8126 Gaithersburg, MD 20898-8126 Tel: (301)251-4925 Fax: (301)251-4911 Tel: (888)205-2311 TDD: (888)205-3223 Internet: http://rarediseases.info.nih.gov/GARD/
Madisons Foundation PO Box 241956 Los Angeles, CA 90024 Tel: (310)264-0826 Fax: (310)264-4766 Email: firstname.lastname@example.org Internet: http://www.madisonsfoundation.org
Autoimmune Information Network, Inc. PO Box 4121 Brick, NJ 08723 Fax: (732)543-7285 Email: email@example.com
PSC Partners Seeking a Cure 5237 South Kenton Way Englewood, CO 80111 Tel: (303)771-5227 Fax: (303)221-0757 Email: firstname.lastname@example.org Internet: http://www.pscpartners.org
European Society for Immunodeficiencies 1-3 rue de Chantepoulet Geneva, CH 1211 Switzerland Tel: 410229080484 Fax: 41229069140 Email: email@example.com Internet: http://www.esid.org
AutoImmunity Community Email: firstname.lastname@example.org Internet: http://www.autoimmunitycommunity.org
CORE 3 St. Andrews Place London, NW1 4LB United Kingdom Tel: 02074860341 Fax: 02072242012 Email: email@example.com Internet: http://www.corecharity.org.uk
For a Complete Report
This is an abstract of a report from the National Organization for Rare Disorders (NORD). A copy of the complete report can be downloaded free from the NORD website for registered users. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational therapies (if available), and references from medical literature. For a full-text version of this topic, go to www.rarediseases.org and click on Rare Disease Database under "Rare Disease Information".
The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only. NORD recommends that affected individuals seek the advice or counsel of their own personal physicians.
It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report
This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.
For additional information and assistance about rare disorders, please contact the National Organization for Rare Disorders at P.O. Box 1968, Danbury, CT 06813-1968; phone (203) 744-0100; web site www.rarediseases.org or email firstname.lastname@example.org
Last Updated: 11/5/2012 Copyright 1986, 1990, 1991, 1994, 1996, 1997, 1999, 2001, 2005 National Organization for Rare Disorders, Inc.
How this information was developed to help you make better health decisions.
Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.