Important It is possible that the main title of the report Progressive Myoclonus Epilepsy is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.
Myoclonic Progressive Familial Epilepsy
Progressive Familial Myoclonic Epilepsy
Epilepsy, Myoclonic Progressive Familial
Myoclonic Epilepsy, Hartung Type
Lafora Disease, Included
Baltic Myoclonus Epilepsy
Lafora Body Disease
Lundborg-Unverricht Disease, Included
Progressive myoclonus epilepsy (PME) is a group of conditions involving the central nervous system and representing more than a dozen different diseases. These diseases share certain features, including a worsening of symptoms over time and the presence of both muscle contractions (myoclonus) and seizures (epilepsy). Patients may have more than one type of seizure, such as petit mal or grand mal. PME is progressive, but the rate of progression may be quick or slow, depending on the underlying disease.
Progressive myoclonus epilepsy (PME) is different from myoclonic epilepsy. In myoclonic epilepsy, the myoclonic jerking motions occur as part of the seizure. In PME, myoclonus occurs separately from seizures, the two respond differently to the same drugs, they evolve differently during the natural history of the disease, and they cause different problems for the patient. Some drugs that are good for seizures, e.g. phenytoin and carbamazepine, may tend to make the myoclonus worse.
Epilepsy Foundation 8301 Professional Place Landover, MD 20785-7223 Tel: (866)330-2718 Fax: (877)687-4878 Tel: (800)332-1000 TDD: (800)332-2070 Email: ContactUs@efa.org Internet: http://www.epilepsyfoundation.org
NIH/National Institute of Neurological Disorders and Stroke P.O. Box 5801 Bethesda, MD 20824 Tel: (301)496-5751 Fax: (301)402-2186 Tel: (800)352-9424 TDD: (301)468-5981 Internet: http://www.ninds.nih.gov/
National Pediatric Myoclonus Center P.O. Box 19643 Springfield, IL 62794-9643 USA Tel: (217)545-7635 Fax: (217)545-1903 Email: email@example.com Internet: http://www.omsusa.org
Epilepsy Canada 2900 John St., Suite 402 Markham Ontario, L3R 5G3 Canada Fax: 9055139461 Tel: 8777340873 Internet: http://www.epilepsy.ca
Genetic and Rare Diseases (GARD) Information Center PO Box 8126 Gaithersburg, MD 20898-8126 Tel: (301)251-4925 Fax: (301)251-4911 Tel: (888)205-2311 TDD: (888)205-3223 Internet: http://rarediseases.info.nih.gov/GARD/
Madisons Foundation PO Box 241956 Los Angeles, CA 90024 Tel: (310)264-0826 Fax: (310)264-4766 Email: firstname.lastname@example.org Internet: http://www.madisonsfoundation.org
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Last Updated: 1/29/2008 Copyright 1990, 1993, 1996, 2002, 2008 National Organization for Rare Disorders, Inc.
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