Important It is possible that the main title of the report Parkinson's Disease is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.
Parkinson's disease is a slowly progressive neurologic condition characterized by involuntary trembling (tremor), muscular stiffness or inflexibility (rigidity), slowness of movement and difficulty carrying out voluntary movements. Degenerative changes occur in areas deep within the brain (substantia nigra and other pigmented regions of the brain), causing a decrease in dopamine levels in the brain. Dopamine is a neurotransmitter, which is a chemical that sends a signal in the brain. Parkinsonian symptoms can also develop secondary to hydrocephalus (a condition in which the head is enlarged and areas of the brain accumulate excessive fluids, resulting in an increase in pressure on the brain), head trauma, inflammation of the brain (encephalitis), obstructions (infarcts) or tumors deep within the cerebral hemispheres and the upper brain stem (basal ganglia), or exposure to certain drugs and toxins. Parkinson's disease is slowly progressive and may not become incapacitating for many years.
WE MOVE (Worldwide Education and Awareness for Movement Disorders) 5731 Mosholu Avenue Bronx, NY 10471 USA Tel: (347)843-6132 Fax: (718)601-5112 Email: firstname.lastname@example.org Internet: http://www.wemove.org
Parkinson's Disease Foundation, Inc. 1359 Broadway Suite 1509 New York, NY 10018 Tel: (212)923-4700 Fax: (212)923-4778 Tel: (800)457-6676 Email: email@example.com Internet: http://www.pdf.org
NIH/National Institute of Allergy and Infectious Diseases Office of Communications and Government Relations 6610 Rockledge Drive, MSC 6612 Bethesda, MD 20892-6612 Tel: (301)496-5717 Fax: (301)402-3573 Tel: (866)284-4107 TDD: (800)877-8339 Email: firstname.lastname@example.org Internet: http://www.niaid.nih.gov/
NIH/National Institute of Neurological Disorders and Stroke P.O. Box 5801 Bethesda, MD 20824 Tel: (301)496-5751 Fax: (301)402-2186 Tel: (800)352-9424 TDD: (301)468-5981 Email: email@example.com Internet: http://www.ninds.nih.gov/
Vasculitis of the Central Nervous System vasculitisoftheCNS@yahoogroups.com Tel: (770)978-5636 Email: firstname.lastname@example.org Internet: http://www.VasculitisoftheCNS@yahoogroups.com
MUMS National Parent-to-Parent Network 150 Custer Court Green Bay, WI 54301-1243 USA Tel: (920)336-5333 Fax: (920)339-0995 Tel: (877)336-5333 Email: email@example.com Internet: http://www.netnet.net/mums/
Alzheimer's Foundation of America 322 8th Ave, 7th Floor New York, NY 10001 USA Tel: (866)232-8484 Fax: (646)638-1546 Tel: (866)232-8484 Email: firstname.lastname@example.org Internet: http://www.alzfdn.org
New Horizons Un-Limited, Inc. 811 East Wisconsin Ave P.O. Box 510034 Milwaukee, WI 53203 USA Tel: (414)299-0124 Fax: (414)347-1977 Email: email@example.com Internet: http://www.new-horizons.org
Genetic and Rare Diseases (GARD) Information Center PO Box 8126 Gaithersburg, MD 20898-8126 Tel: (301)251-4925 Fax: (301)251-4911 Tel: (888)205-2311 TDD: (888)205-3223 Internet: http://rarediseases.info.nih.gov/GARD/
Madisons Foundation PO Box 241956 Los Angeles, CA 90024 Tel: (310)264-0826 Fax: (310)264-4766 Email: firstname.lastname@example.org Internet: http://www.madisonsfoundation.org
American Association of Neurological Surgeons 5550 Meadowbrook Drive Rolling Meadows, IL 60008-3852 Tel: (847)378-0500 Fax: (847)378-0600 Tel: (888)566-2267 Email: email@example.com Internet: http://www.NeurosurgeryToday.org and http://www.aans.org
Child Neurology Foundation 2000 West 98th Street Bloomington, MN 55431 USA Tel: (952)641-6100 Fax: (952)881-6276 Tel: (877)263-5430 Email: firstname.lastname@example.org Internet: http://www.childneurologyfoundation.org
Northwest Parkinson's Foundation 400 Mercer Street #401 Seattle, WA 98109 Tel: (206)748-9481 Tel: (877)980-7500 Email: email@example.com Internet: http://www.nwpf.org
Bachmann-Strauss Dystonia & Parkinson Foundation 551 Fifth Avenue Suite 520 New York, NY 10176 Tel: (212)682-9900 Fax: (212)682-6156 Internet: http://www.dystonia-parkinson.org
Movement Disorder Society 555 E. Wells Street Suite 1100 Milwaukee, WI 53202-3823 Tel: (414)276-2145 Fax: (414)276-3349 Email: firstname.lastname@example.org Internet: http://www.movementdisorders.org
For a Complete Report
This is an abstract of a report from the National Organization for Rare Disorders (NORD). A copy of the complete report can be downloaded free from the NORD website for registered users. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational therapies (if available), and references from medical literature. For a full-text version of this topic, go to www.rarediseases.org and click on Rare Disease Database under "Rare Disease Information".
The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only. NORD recommends that affected individuals seek the advice or counsel of their own personal physicians.
It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report
This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.
For additional information and assistance about rare disorders, please contact the National Organization for Rare Disorders at P.O. Box 1968, Danbury, CT 06813-1968; phone (203) 744-0100; web site www.rarediseases.org or email email@example.com
Last Updated: 4/7/2008 Copyright 1986, 1987, 1988, 1990, 1991, 1992, 1993, 1994, 1995, 1996, 1997, 1998, 1999, 2000, 2001 National Organization for Rare Disorders, Inc.
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