Important It is possible that the main title of the report Multiple Sclerosis is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.
primary progressive multiple sclerosis
relapsing-remitting multiple sclerosis
Multiple sclerosis is a chronic neuroimmunologic (both the nervous system and the immunological system are involved) disorder of the central nervous system involving the brain, spinal cord and optic nerves. By means of a mechanism not clearly understood, the protective fatty, insulating substance called myelin sheath that covers the nerve is destroyed. The inflammatory attacks that produce the characteristic scarring (plaques or patches) of the myelin sheath occurs randomly, vary in intensity, and at multiple sites. The course of the disease may advance, relapse, remit, or stabilize. The randomness of the location of plaques or patches affects the nerve's ability to transmit information (neurotransmission) and causes a wide range of neurological symptoms, which may vary from person to person.
Recently it has been learned that the nerve fibers themselves, (axons), in addition to the myelin sheaths, are affected by the neuroimmunologic attacks. Damage to the nerve cells may be irreversible. As a result, clinicians recommend early intervention with one of the disease-modifying agents (see below).
WE MOVE (Worldwide Education and Awareness for Movement Disorders) 5731 Mosholu Avenue Bronx, NY 10471 USA Tel: (347)843-6132 Fax: (718)601-5112 Email: firstname.lastname@example.org Internet: http://www.wemove.org
National Multiple Sclerosis Society 1100 New York Avenue NW Suite 660 Washington, DC 20005-3934 USA Tel: (202)408-1500 Fax: (202)408-0696 Tel: (800)344-4867 Email: email@example.com Internet: http://www.nationalmssociety.org
American Autoimmune Related Diseases Association, Inc. 22100 Gratiot Ave. Eastpointe, MI 48021 Tel: (586)776-3900 Fax: (586)776-3903 Tel: (800)598-4668 Email: firstname.lastname@example.org Internet: http://www.aarda.org/
NIH/National Institute of Neurological Disorders and Stroke P.O. Box 5801 Bethesda, MD 20824 Tel: (301)496-5751 Fax: (301)402-2186 Tel: (800)352-9424 TDD: (301)468-5981 Internet: http://www.ninds.nih.gov/
Consortium of Multiple Sclerosis Centers 359 Main Street Suite A Hackensack, NJ 07601 Tel: (201)487-1050 Fax: (201)678-2290 Email: email@example.com Internet: http://www.mscare.org
Multiple Sclerosis Association of America 706 Haddonfield Road Cherry Hill, NJ 08002 USA Tel: (856)488-4500 Fax: (856)661-9797 Tel: (800)532-7667 Email: firstname.lastname@example.org Internet: http://www.msassociation.org/
Multiple Sclerosis International Federation 3rd Floor Skyline House 200 Union Street London, SE1 0LX United Kingdom Tel: 4402076201911 Fax: 4402076201922 Email: email@example.com Internet: http://www.msif.org/en/
Spastic Paraplegia Foundation 5305 Miramar Ln Colleyville, TX 76034 USA Tel: (877)773-4483 Email: firstname.lastname@example.org Internet: http://sp-foundation.org
Christopher & Dana Reeve Foundation 636 Morris Turnpike, Suite 3A Short Hills, NJ 07078 USA Tel: (973)379-2690 Fax: (973)912-9433 Tel: (800)225-0292 Email: prc@ChristopherReeve.org Internet: http://www.christopherreeve.org
New Horizons Un-Limited, Inc. 811 East Wisconsin Ave P.O. Box 510034 Milwaukee, WI 53203 USA Tel: (414)299-0124 Fax: (414)347-1977 Email: email@example.com Internet: http://www.new-horizons.org
Genetic and Rare Diseases (GARD) Information Center PO Box 8126 Gaithersburg, MD 20898-8126 Tel: (301)251-4925 Fax: (301)251-4911 Tel: (888)205-2311 TDD: (888)205-3223 Internet: http://rarediseases.info.nih.gov/GARD/
Madisons Foundation PO Box 241956 Los Angeles, CA 90024 Tel: (310)264-0826 Fax: (310)264-4766 Email: firstname.lastname@example.org Internet: http://www.madisonsfoundation.org
Autoimmune Information Network, Inc. PO Box 4121 Brick, NJ 08723 Fax: (732)543-7285 Email: email@example.com
European Society for Immunodeficiencies 1-3 rue de Chantepoulet Geneva, CH 1211 Switzerland Tel: 410229080484 Fax: 41229069140 Email: firstname.lastname@example.org Internet: http://www.esid.org
Multiple Sclerosis Foundation 6520 North Andrews Avenue Ft. Lauderdale, FL 33309-2130 Tel: (954)776-6805 Fax: (954)938-8708 Tel: (800)225-6495 Email: email@example.com Internet: http://www.msfocus.org
AutoImmunity Community Email: firstname.lastname@example.org Internet: http://www.autoimmunitycommunity.org
PLAN Institute for Caring Citizenship Suite 260 - 3665 Kingsway Vancouver British Columbia, V5R 5W2 Canada Tel: 6044399566 Fax: 6044397001 Email: email@example.com Internet: http://www.planinstitute.ca/?q=learnfromus/library
Child Neurology Foundation 201 Chicago Ave, #200 Minneapolis, MN 55415 USA Tel: (952)641-6100 Fax: (952)881-6276 Tel: (877)263-5430 Email: firstname.lastname@example.org Internet: http://www.childneurologyfoundation.org
For a Complete Report
This is an abstract of a report from the National Organization for Rare Disorders (NORD). A copy of the complete report can be downloaded free from the NORD website for registered users. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational therapies (if available), and references from medical literature. For a full-text version of this topic, go to www.rarediseases.org and click on Rare Disease Database under "Rare Disease Information".
The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only. NORD recommends that affected individuals seek the advice or counsel of their own personal physicians.
It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report
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