Important It is possible that the main title of the report Classic Hereditary Hemochromatosis is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.
hemochromatosis type I
Hereditary hemochromatosis is a general term for several rare genetic disorders that are characterized by the accumulation of iron in various organs of the body such as the liver, heart and pancreas. The abnormally stored iron can damage affected organs, potentially causing a variety of different symptoms. The most common form of hemochromatosis is known by several different names including hemochromatosis type I, HFE-related hemochromatosis, hereditary hemochromatosis and classic hereditary hemochromatosis. Iron accumulation in classic hereditary hemochromatosis occurs slowly over many years. Eventually, iron accumulation causes tissue damage and impaired functioning of affected organs. In many cases, symptoms may not become apparent until some point between 40-60 years of age. Onset is usually earlier for men compared to women. Common symptoms include abdominal pain, weakness, lethargy, and unintended weight loss. Without treatment, classic hereditary hemochromatosis can progress to cause serious, life-threatening complications including failure of affected organs.
There are several different disorders associated with excess iron accumulation in the body. Collectively, these different disorders are grouped under the name iron overload disorders. These disorders are caused by mutations to different genes and have different clinical presentations. Classic hereditary hemochromatosis is caused by mutations of the HFE gene. This report primarily deals with classic hereditary hemochromatosis caused by mutation of the HFE gene.
Iron Overload Diseases Association, Inc. 525 Mayflower Road West Palm Beach, Fl 33405 Tel: (561)586-8246 Fax: (561)842-9881 Tel: (866)768-8629 Email: firstname.lastname@example.org Internet: http://ironoverload.org
American Liver Foundation 39 Broadway, Suite 2700 New York, NY 10006 USA Fax: (212)483-8179 Tel: (800)465-4837 Email: http://www.liverfoundation.org/contact/ Internet: http://www.liverfoundation.org
NIH/National Institute of Diabetes, Digestive & Kidney Diseases Office of Communications & Public Liaison Bldg 31, Rm 9A06 31 Center Drive, MSC 2560 Bethesda, MD 20892-2560 Tel: (301)496-3583 Email: NDDIC@info.niddk.nih.gov Internet: http://www2.niddk.nih.gov/
Canadian Hemochromatosis Society 7000 Minoru Boulevard Suite 285 Richmond British Columbia, V6Y 3Z5 Canada Tel: 6042797135 Fax: 6042797138 Tel: 8772234766 Email: email@example.com Internet: http://www.toomuchiron.ca
American Hemochromatosis Society 4044 W. Lake Mary Blvd. Suite 104 PMB 416 Lake Mary, FL 32746-2012 USA Tel: (407)829-4488 Fax: (407)333-1284 Tel: (888)655-4766 Email: firstname.lastname@example.org Internet: http://www.americanhs.org
Iron Disorders Institute PO Box 675 Taylors, SC 29687 USA Tel: (864)292-1175 Fax: (864)292-1878 Tel: (888)565-4766 Email: email@example.com Internet: http://www.irondisorders.org
Genetic and Rare Diseases (GARD) Information Center PO Box 8126 Gaithersburg, MD 20898-8126 Tel: (301)251-4925 Fax: (301)251-4911 Tel: (888)205-2311 TDD: (888)205-3223 Internet: http://rarediseases.info.nih.gov/GARD/
Madisons Foundation PO Box 241956 Los Angeles, CA 90024 Tel: (310)264-0826 Fax: (310)264-4766 Email: firstname.lastname@example.org Internet: http://www.madisonsfoundation.org
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It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report
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