Important It is possible that the main title of the report Cushing Syndrome is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.
endogenous Cushing syndrome
exogenous Cushing syndrome
Summary Cushing syndrome is a rare endocrine disorder characterized by a variety of symptoms and physical abnormalities that occur due to excessive amounts of the hormone cortisol, a type of glucocorticoid. Glucocorticoids are a class of steroid hormones that are important in the regulation of the metabolism of glucose and also modulate the response to stress. Cushing syndrome most commonly affects adults between the ages of 25 to 40. It can be caused by prolonged exposure to elevated levels of glucocorticoids produced within the body (endogenous) or introduced from outside the body (exogenous). Symptoms can include upper body obesity, a rounded face, thin purple streaks (purple striae) which occur on the skin, increased fat around the neck, and slender arms and legs. Children with Cushing syndrome are typically obese with slowed growth rates.
Introduction In 1912, Harvey Cushing described a patient with hypercorticism but assumed it to be a polyglandular disorder. The cause was disputed for almost 40 years. Cushing disease, which is pituitary adrenocorticotropin hormone (ACTH) dependent Cushing syndrome, was first described by Dr. Cushing in 1932. Though pituitary surgery was introduced in the early 20th century, it was not until 1933 that neurosurgery was performed on the first patient with Cushing disease.
National Adrenal Diseases Foundation 505 Northern Bloulevard Great Neck, NY 11021 USA Tel: (516)487-4992 Fax: (516)829-5710 Email: firstname.lastname@example.org Internet: http://www.nadf.us/
Cushing's Support and Research Foundation, Inc. 60 Robbins Rd 12 Plymouth, MA 02360 Tel: (617)723-3674 Fax: (617)723-3674 Email: email@example.com Internet: http://www.csrf.net
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Autoimmune Information Network, Inc. PO Box 4121 Brick, NJ 08723 Fax: (732)543-7285 Email: firstname.lastname@example.org
European Society for Immunodeficiencies 1-3 rue de Chantepoulet Geneva, CH 1211 Switzerland Tel: 410229080484 Fax: 41229069140 Email: email@example.com Internet: http://www.esid.org
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It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report
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