Important It is possible that the main title of the report Leiomyosarcoma, Inferior Vena Cava is not the name you expected.
Leiomyosarcoma of the inferior vena cava is an extremely rare malignant (cancerous) tumor arising from the smooth muscle lining the walls of the large vein that carries blood from the lower body to the heart (inferior vena cava). There are essentially two types of muscles in the body - voluntary and involuntary. Smooth muscles are involuntary muscles - the brain has no conscious control over them. Smooth muscles react involuntarily in response to various stimuli. For example, the smooth muscle in walls of blood vessels contracts to help regulate blood flow.
Leiomyosarcomas are a form of cancer. The term "cancer" refers to a group of diseases characterized by abnormal, uncontrolled cellular growth that invades surrounding tissues and may spread (metastasize) to distant bodily tissues or organs via the bloodstream, the lymphatic system, or other means. Different forms of cancer, including leiomyosarcomas, are graded according to certain histological parameters evaluated microscopically and this grade (low, intermediate, or high) gives the clinician an indication of the potential clinical aggressiveness of the tumor.
Leiomyosarcoma is classified as a soft tissue sarcoma. Sarcomas are malignant tumors that arise from the connective tissue, which connects, supports and surrounds various structures and organs in the body. Soft tissue includes fat, muscle, nerve, tendons, tissue surrounding the joints (synovial tissue), and blood and lymph vessels. The exact cause of sarcomas including leiomyosarcomas is unknown.
American Cancer Society, Inc. 250 Williams NW St Ste 6000 Atlanta, GA 30303 USA Tel: (404)320-3333 Tel: (800)227-2345 TDD: (866)228-4327 Internet: http://www.cancer.org
National Cancer Institute 6116 Executive Blvd Suite 300 Bethesda, MD 20892-8322 USA Tel: (301)435-3848 Tel: (800)422-6237 TDD: (800)332-8615 Email: email@example.com Internet: http://www.cancer.gov
OncoLink: The University of Pennsylvania Cancer Center Resource 3400 Spruce Street 2 Donner Philadelphia, PA 19104-4283 USA Tel: (215)349-8895 Fax: (215)349-5445 Email: firstname.lastname@example.org Internet: http://www.oncolink.upenn.edu
Sarcoma Foundation of America 9899 Main Street Ste 204 Damascus, MD 20872 USA Tel: (301)253-8687 Fax: (301)253-8690 Email: email@example.com Internet: http://www.curesarcoma.org
Sarcoma Alliance 775 E. Blithedale #334 Mill Valley, CA 94941 USA Tel: (415)381-7236 Fax: (415)381-7235 Email: firstname.lastname@example.org Internet: http://www.sarcomaalliance.org
Rare Cancer Alliance 1649 North Pacana Way Green Valley, AZ 85614 USA Internet: http://www.rare-cancer.org
Northwest Sarcoma Foundation P.O. Box 91460 Portland, OR 97291 Tel: (503)954-5740 Email: email@example.com Internet: http://www.nwsarcoma.org
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This is an abstract of a report from the National Organization for Rare Disorders (NORD). A copy of the complete report can be downloaded free from the NORD website for registered users. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational therapies (if available), and references from medical literature. For a full-text version of this topic, go to www.rarediseases.org and click on Rare Disease Database under "Rare Disease Information".
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For additional information and assistance about rare disorders, please contact the National Organization for Rare Disorders at P.O. Box 1968, Danbury, CT 06813-1968; phone (203) 744-0100; web site www.rarediseases.org or email firstname.lastname@example.org
Last Updated: 8/2/2010 Copyright 2010 National Organization for Rare Disorders, Inc.
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